Tadalafil and Nitrate Do Not Mix

Generic tadalafil is one of the most popular drugs recently used to treat men who are suffering the conditions of erectile dysfunction. However, combining generic tadalafil with other chemicals, such as nitrates can be very dangerous. Drug interaction could either provide complications on your recent health condition, or can even be fatal. If you are planning to take generic tadalafil, make sure to tell your doctor about the other drugs or chemicals you are currently using to save you from any risks.

Generic tadalafil is basically a type of PDE5 inhibitor used for treating erectile dysfunction. The drug works by inhibiting the enzymes activities from converting certain chemicals which can constrict the muscle tissue surrounding the penile area. Generic tadalafil therefore help patients with ED by relaxing these smooth muscles to allow more blood supply towards the penis during sexual excitement. However, it is not effective when you are not sexually aroused. The drug can only help you prolong erection, but does not permanently treat your erection problems.

Nitrates, on the other hand, are medicines administered to patients who are suffering angina or chest pain caused by coronary artery disease. Drugs containing nitrates belong to the group of vasodilators which helps the blood vessels to widen. Examples of these are nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate. Nitrates widen the blood vessels in the body to accommodate more blood flow during an angina attack. People with heart problems usually experience chest pain due to the narrowing of the arteries which can impede normal blood flow as well as enough supply of the oxygen. Moreover, fatty plaque which has been built up around the artery lining is said to be the root cause of angina. With nitrates, the widened arteries can help the heart pump enough blood to deliver all the necessary nutrients and oxygen around the body. Nitrates can be taken for short term purposes, such as relieving angina anytime as needed and preventing the attacks of angina before engaging into any activities that can trigger the condition. For long term purposes, nitrates are taken daily to lessen or prevent angina attacks.

If you have been advised by your doctor to take nitrates for your heart problems, you should never take ED drugs like generic tadalafil. As you can see, both drugs aim to relax the smooth muscles to allow more blood flow. If taken together, this can cause excess vasodilation and lead to a condition termed as hypotension or a decrease in blood pressure. A low blood pressure can be life-threatening if not treated immediately.

If you are currently experiencing other health issues, it is therefore critical for you to consult your doctor before you pursue on any medications for erectile dysfunction. Provide your doctor a list of all the medications you are currently taking, as well as your history of diseases, if any. If your doctor advices you not to engage in sexual activities to avoid other health complications, then it is best to heed his advice.


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